GAMMA E TOCOPHEROL – Life Extension 60 Softgels – With Sesame Lignans

Gamma E Tocopherol – The primary purpose of supplementing with vitamin E is to suppress damaging free radicals. Scientific studies have identified the gamma-tocopherol form of vitamin E as being critical to human health.

New research shows that sesame lignans increase gamma-tocopherol levels in the body while reducing free radical damage. In response to these findings, Life Extension has reformulated the popular Gamma E Tocopherol supplement to replace tocotrienols with sesame lignans.

On August 11, 2004, JAMA published an extensive review article extolling the benefits of gamma-tocopherol. In its article, JAMA discusses the inconsistent findings about alpha-tocopherol and presents compelling evidence that gamma-tocopherol is the form of vitamin E most likely to reduce the risk of degenerative disease.

The JAMA article reviewed the scientific basis for vitamin E’s cardioprotective effects. It then went on to describe why studies that showed no efficacy to vitamin E supplementation might have been flawed. The reasons cited for why these studies failed to provide reliable results include selection of subjects, stage of disease, end points, dosage, and source of the vitamin E. Another issue raised in the JAMA review is that vitamin E’s mechanism of preventing heart disease is most likely related to its ability to suppress LDL oxidation. A more targeted approach, JAMA asserts, would be to include only patients with enhanced levels of oxidative stress and low plasma levels of vitamin E in order to determine those most likely to benefit from antioxidant treatment.

A wide range of toxic factors including excess blood levels of homocysteine, C-reactive protein, fibrinogen, insulin, glucose, and triglycerides causes atherosclerotic heart disease. It is impractical to expect vitamin E by itself to prevent atherosclerosis. If healthy arteries are to be maintained, other pathological mechanisms have to be addressed as well.